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The AhR is ligand-activated transcription factor that responds to endogenous ligands in addition to exogenous xenobiotic ligands, such as PAHs ( Glutathione, an important antioxidant is involved in the elimination of PAHs and spermatozoa depend heavilyon glutathione metabolizing system for its survival ( 5 Conclusion The present findings surmise the adverse impact of environment borne PAHs exposure on sperm function in idiopathic infertility which are largely ignored in regular infertility assessment

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As well, treatment with alogliptin (20 mg/kg/day), a selective DPP-4 inhibitor, showed similar anti-inflammatory effects in the injured arteries of low-density lipoprotein receptor-deficient mice [69]

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