Based in Boca Raton, Florida, the brand uses HDPE for all its packaging, one of the most commonly and easily recycled forms of plastic (so make sure you recycle after use!)
Crucially, GIPR co-activation also appears to reduce some of the GI tolerability friction that single-receptor GLP-1R agonism can produce which in research terms translates to better subject retention in longer-duration studies
In Phase 3 TRIUMPH-4 (Eli Lilly, December 11, 2025), the 12 mg arm averaged 28.7% body weight loss at 68 weeks
Claxton AJ, Cramer J, Pierce CA
Unfortunately two phase I studies of the anti-IFN antibody AMG811 in the treatment of mild to moderate systemic and cutaneous lupus (113) showed safety with favorable immunogenicity profile but did not show significant therapeutic effect despite decreasing IFN-related gene expression (114)
Cell 166 , 867880 (2016)