Because they oxidize protein and lipid molecules as well as damage DNA
However, there is an effective medical solution you may not be aware of
The 1GP1 active site model was curated by identifying key amino acids that surround the active site known to have roles in catalysis and substrate or inhibitor binding (GLN140 (glutamine), ARG177 (arginine), SEC45 (selenocysteine) and ARG50 (arginine)), as no bound ligand was present [22, 33,34,35,36,37,38]
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Routine lab testing can be a barrier to care for some patients who cannot take off work or arrange transportation to visit an in-person clinic or phlebotomist
These exclude many patients, including Medicare and Medicaid enrollees
