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Tirzepatide is a dual GIP/GLP-1 receptor agonist , which means it also targets another gut hormone called GIP (glucose-dependent insulinotropic polypeptide)

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no additional dose adjustment is usually necessary

Tirzepatide initiates appetite suppression within 2472 hours of your first injection as GLP-1 and GIP receptors engage in the hypothalamus and brainstem

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Ge, Y., Konrad, M