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Description AOD 9604 Treatment for Fat Burning, Metabolism & Weight Loss AOD 9604, often referred to as the fat-burning peptide, is a synthetic derivative of human growth hormone (HGH) designed to promote fat loss without influencing insulin-like growth factor 1 (IGF-1) production

Strongest human evidence The METAOD006 (OPTIONS) Phase 2b trial randomized 502 adults with obesity (BMI 30-45 kg/m^2) to oral AOD-9604 (0.25, 0.5, or 1 mg/day) or placebo for 24 weeks alongside a supervised diet and exercise program

By upregulating beta-3 adrenergic receptors and directly triggering lipolytic pathways, the peptide can enhance fat mobilization from typically resistant areas

This mechanism supports regeneration across muscle, skin, and connective tissues 2

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British National Formulary (BNF)