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So, in summary: FOXO4-DRI appears to represent the next-generation senolytic, offering improved specificity, but it is still earlier stage than many small-molecule senolytics or repurposed drug combinations

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Kyowa Hakko mastered the craft with Setria, but the industry is always trying to find ways to get it into the cells more effectively and rapidly, especially in water-based environments

This selective action reduces the risk of side effects and makes it a more predictable therapeutic option

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