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These differ from regular lotions or creams, which tend to be lighter and absorb quickly

Severe or persistent dermal reactions represent a smaller subset and typically warrant dose adjustment or temporary treatment interruption

343 Supplements like Metanx , which contains L-methylfolate, methylcobalamin, and pyridoxal-5-phosphate, have improved symptoms by enhancing endothelial function and restoring neurotrophic support

Furthermore, drug-loaded nanocarriers allow for controlled, sustained, and localized release of chemotherapeutics, immunomodulators, or molecular-targeted agents, synchronizing therapeutic activity with radiation delivery and overcoming temporal limitations of conventional systemic administration [215]