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This hierarchical PQC system integrates molecular chaperones, ubiquitinproteasome systems, mitochondrial unfolded protein response (UPRmt), ATP-dependent proteases, mitochondrial-derived vesicles, and mitophagy pathways [6]

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Glycine and serine (serine is converted to glycine for GSH synthesis) are spent making GSH, but glutamate is increased once GSH exits the cell and is transaminated by GGT, releasing glutamate into circulation

HIV-associated antiretroviral toxic neuropathy (ATN): a review of recent advances in pathophysiology and treatment