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Patients with higher baseline body mass index (BMI) or more severe insulin resistance may experience different response patterns compared to those with milder metabolic dysfunction

Persistent injection-site reactions such as ongoing redness, swelling, or pain should be reported to a GP or diabetes specialist nurse promptly

If reactions persist for more than 48 hours, document them with photos to share with your healthcare provider

A meaningful minority has more significant issues

GLP-1 drug usage was associated with a reduced risk of just about everything bad: substance use and psychotic disorders, seizures, neuro-cognitive disorders (including Alzheimers disease and dementia), coagulation disorders [e.g., means clotting], cardio-metabolic disorders, infectious illnesses and several respiratory conditions. When I initially read this study in January, it seemed too good to be true

Retatrutide for managing overweight and obesity [GID-TA11845]