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The research initially aimed to map bitter-taste receptors in the human gut to naturally trigger the release of appetite-suppressing hormones

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Participants were randomised (4:1) to receive once-weekly subcutaneous injections of HRS9531 or placebo titrating up to the target dose of 8mg over a 24-week period and then maintaining that dose for 12 weeks

However, it has also been found to be effective in aiding weight loss

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Patients In 138 AI patients referred to our unit, 101 patients were enrolled