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is a participant in the BIH Charit Clinician Scientist Program funded by the CharitUniversittsmedizin Berlin, and the Berlin Institute of Health at Charit (BIH)

Upon production and release, endocannabinoids bind to cannabinoid receptors located on pre-synaptic membranes and change neuronal excitability by modulating the release of different neurotransmitters 8,9,10,11

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Age and obesity are high-risk factors for kidney disease (35, 36)

This peroxidation occurs via two major pathways: the enzymatic pathway, mediated by lipoxygenases (LOXs), cytochrome P450 oxidoreductase (POR), and NADPH oxidases (NOXs), promotes the generation of PUFA-PL-OOHs, leading to the accumulation of reactive aldehydes, ketones, and other toxic metabolites, ultimately disrupting membrane integrity and triggering ferroptosis (Maheshwari, 2023)

-GLP-1 -neogenesis (Rachmany ' -Age 2013)