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In gastric cancer, the effect of two introns of the GPX3 gene, namely rs3805435 and rs3828599, on gene expression and disease susceptibility has been demonstrated (26)

These findings suggest that the compound was released from the tissues and bio-transformed into CO which increased the accumulation of COHb in blood

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It has been shown to inhibit inflammatory pathways, reducing the phosphorylation of NF-B p65, a key mediator of inflammation

However, patients with existing cardiovascular conditions should discuss any concerns with their healthcare provider