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however, in rare cases it has been associated with a form of kidney injury called oxalate nephropathy, so people with pre-existing kidney disease should discuss this risk with their GP before use

53, 54 One study of mitochondrial dysfunction in the autism brain found decreased protein levels of multiple ETC complexes in the cerebellum, frontal and temporal cortex

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The purified TRF1 TRFH domain was then concentrated by centrifugation on a Vivaspin Turbo 15 centrifugal concentrator (10 kDa MWCO) to either ~ 3 mg/mL for NMR studies or ~ 30 mg/mL for crystallisation before flash-freezing and storage at 80 C (Supplementary Fig