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Appetite suppression, blood glucose control and increased energy expenditure operate simultaneously, amplifying the weight-loss effect.

Long-term safety data continues to accumulate, and a comprehensive 2024 review in Diabetes Care by Daniel Drucker concluded that the overall risk-benefit profile of GLP-1 medicines remains favorable for their approved indications

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Archived from the original on 18 June 2025

India is home to over 100 million people with diabetes and approximately 250 million classified as obese or overweight.[15] What makes the situation uniquely dangerous is the Thin-Fat Indian paradox: South Asians tend to accumulate more visceral (belly) fat, liver fat, and less lean muscle mass at lower body weights than Western populations.[8][9][10] While GLP-1 medications are a global phenomenon, they are particularly critical for the Thin-Fat Indian phenotype

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