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& Nimmesgern, E

Clinical data from semaglutide trials shows average heart rate increases of 2-5 beats per minute, though individual responses vary widely

The supporting adult trials enrolled participants with a BMI of 30 kg/m or greater, or 27 to 29.9 kg/m with at least one weight-related condition such as hypertension or dyslipidemia

After filling out a short form, eligible individuals are approved automatically within seconds

Individual variability in response to retatrutide is well recognised in clinical research

If approved, Novo Nordisk has indicated theyll have US manufacturing ready. Orforglipron is still completing its phase three trials, John adds, and results are expected in the first quarter of 2026