Bottom line The FDA strongly recommends using an FDA-approved semaglutide drug like Ozempic when it is available instead of compounded semaglutide
While Basaglar can be prescribed for both type 1 and type 2 diabetes in adults and also in children aged 6+, Ozempic, however, is only approved for type 2 diabetes & isnt an option for people with type 1 diabetes TL;DR Basaglar (insulin glargine) and Ozempic (semaglutide) treat type 2 diabetes through completely different mechanisms Basaglar is a long acting basal insulin injected daily that directly replaces insulin your body lacks while Ozempic is a GLP 1 receptor agonist injected weekly that enhances your bodys natural insulin production Key differences: Ozempic promotes weight loss (10-15%) while Basaglar often causes weight gain Ozempic reduces A1C by 1.4-1.8% vs Basaglars 0.8-1.5%
[archived link] Link to Original Substack Post
According to Saman Rahmanian, Ros co-founder and chief product officer, the Super Bowl strategy is the second phase of a narrative arc that began when Williams partnered with the brand in 2025
PloS One (2017) 12(8):e0183541
The most important unknowns (cardiovascular safety, evidence on hard kidney outcomes, head-to-head tirals etc) all report between now and 2028