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* **General Recommendation:** Due to the **lack of safety data**, the use of Tirzepatide (Zepbound) is **generally not recommended while breastfeeding.** Healthcare providers typically advise against using medications with unknown infant effects during lactation unless there is a compelling medical need for the mother that outweighs the potential, unknown risks to the baby

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A skeletal developmental disorder, KBD has been reported in low-selenium areas of China, North Korea, and the Siberian region of Russia, and can be alleviated by selenium supplementation