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427,428,429 The compound NLY01 is particularly effective at attenuating the activity of proinflammatory microglia and preventing the transformation of astrocytes to a reactive phenotype

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[see Adverse Reactions (6.1), Drug Interactions (7.2)]

33,34 It neutralizes reactive oxygen species, chelates metal ions, acts as an inducer of endogenous antioxidants, and reduces oxidized forms of other antioxidants, including vitamins C, E, and glutathione

Jones and Brierley describe obesity as a chronic, relapsing, and progressive disease