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Studies using proliferating melanocyte cultures showed that estrogen receptor alpha (ER) complexes interact with melanocyte-specific transcription factors to regulate melanogenic genes, which leads to hyperpigmentation as seen in pigmentation disorders associated with elevated estrogen levels [50]

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Pooled fractions were equilibrated to 25 mM Histidine, 7% Sucrose, 0.02% polysorbate 80, pH 6.0 by tangential flow filtration using a 30 kDa cut-off filter

Value of serum iron levels in assessing effect of haematinics in the macrocytic anaemias

Testing before and during supplementation can help providers assess efficacy, though clinical significance varies by individual and condition

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