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Tirzepatide is the right choice when the research question involves GIPR biology, GIP-GLP-1 synergy, or the pharmacology of dual-agonist engineering itself

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Diabetes (2014) 63(2):48393.10.2337/db13-0954 46 Delgado-ArosSVellaACamilleriMLowPABurtonDDThomfordeGMet alEffects of glucagon-like peptide-1 and feeding on gastric volumes in diabetes mellitus with cardio-vagal dysfunction

For practices and PCNs, the tirzepatide vs semaglutide question is best answered through eligibility, safety and pathway suitability rather than weight loss data alone

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For example, "Felt nauseous around 10 a.m., skipped lunch, better by 3 p.m." is enough