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Its global status is that of an investigational, research-only chemical

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While the comproportionation reaction is a well reported redox cycling chemical mechanism, in this instance the triad model does not require the additional comproportionation reaction to accurately replicate the experimental OCR profile, suggesting that the comproportionation reaction is not mechanistically integral to the production of ROS through a quinone-based redox cycle

Tan S, Schubert D, Maher P

People experiencing fatigue: B12 plays a role in energy production, and supplementation may help alleviate fatigue

Figure creation: FH