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We summarize the main environmental and ecological factors that can influence the host-parasite interaction in polluted environments (Figure 2), including (i) the type of pollutants mixture, their probabilities of occurrence, and their chemical properties (accumulation, metabolization, differential toxicity among species, etc.), (ii) the nature and intensity of parasites, tolerance to pollutants, the ability to sequester pollutants, life cycle (number of obligatory hosts), diversity of parasites species, and dynamics of co-infection, and (iii) host tolerance and resistance to parasites, tolerance to pollutants, individual traits (sex, age, body length, trophic ecology, etc.), and inter- and intra-specific relationships

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