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The high rate of additional anti-diabetic medication use may have lead to an over-estimation of treatment effect in some of the treatment groups, such as semaglutide 3 mg

(2) WT group: wild type mice were treated with APAP (suspended in saline solution, in a final volume of 0.25 mL) through intraperitoneal injection (i.p)

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In addition, we did not observe compelling evidence for additional independent associations within the locus (Extended Data Fig