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DOI: 10.1111/jocd.70670

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Compound Reference Data Compound: Epithalon CAS Number: 307297-39-8 Molecular Formula: C14H22N4O9 Molecular Weight: 390.35 g/mol Sequence: Ala-Glu-Asp-Gly (AEDG) Synonyms: Epitalon, Epithalone, AEDG peptide, Khavinson tetrapeptide Selected Published Studies The following peer-reviewed studies were conducted using animal models or in vitro cell-culture systems

It is proposed that the non-ubiquitinated NRF2 would remain bound to the KEAP1-Cul3 complex and therefore prevent the newly translated NRF2 from inhibition by the E3-ubiquitin complex, thereby promoting NRF2 accumulation in the nucleus [17]