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Microbiome-mediated upregulation of MicroRNA-146a in sporadic Alzheimers disease

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Liraglutide at 3.0 mg produced mean reductions near 8% in major trials, clinically meaningful but smaller than the newer agents effects

Nature 620 , 480 (2023)

Can the available structural information on AR-ligand interactions based on x-ray crystallography and modeling be exploited for the rational design of next-generation antiandrogens to overcome problems with antiandrogen resistance