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FIGURE 2 In addition to IGF-1R, insulin-like growth factor binding proteins (IGFBPs) are also required for IGF-1 bioavailability because they interact with IGF-1 with the same affinity as IGF-1R (Perks, 2023)

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Matsuyama, T., Yoshinaga, S

Steven Libutti, as a clinical co-leader on this project

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