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When there is too much iron in the body, excess iron can be deposited in tissues and organs, produce lipid peroxidation, affects cell damage, which can lead to cancer, hematological diseases, and other chronic and commonly encountered diseases

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Compared to the liver, we observed that the kidney has: (1) similar increased use of energy-related metabolites and production of urea cycle and ammonia-related intermediates, suggesting a shared catabolism in AKI, and (2) higher pools of energy metabolism intermediates in AKI

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As the only cells that form bone are osteoblasts, the activity of osteoblasts is of utmost importance