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The first patient was a 64-year-old man from Rio Grande do Sul, Brazil, who developed congestive heart failure with bilateral pulmonary infiltrates and pleural effusion on chest X-ray in June 2016

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In contrast to dithiol glutaredoxins and ScGrx6/7, other monothiol glutaredoxins from a variety of sources do not possess an enzymatic activity in these assays 25,26,27,28,29

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Agirman G, Yu KB, Hsiao EY (2021) Signaling inflammation across the gut-brain axis

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