Rab1A over-expression prevents Golgi apparatus fragmentation and partially corrects motor deficits in an alpha-synuclein based rat model of Parkinsons disease
Traditional GLP-1 weight loss drugs like Wegovy (semaglutide) or Mounjaro/Zepbound (tirzepatide) often result in muscle loss, which can adversely affect overall health outcomes
Symons TB, Vandervoort AA, Rice CL, Overend TJ, Marsh GD
In a well designed, prospective, placebo-controlled study 695 T2DM patients inadequately controlled on maximum doses of metformin randomly were assigned to receive dapagliflozin alone (n=233), exenatide alone (n=231), or dapagliflozin plus exenatide (n=231) for 28 weeks (60) (Table 1)
Jakobsdottir et al., 2016)
Most people start their liraglutide journey with a low dose, which gently increases each week