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Sample Preparation Desalting and buffer exchange Enzymatic digestion for peptide mapping Minimizing peptide adsorption and degradation Proper sample preparation helps prevent contamination and reduces signal suppression during LC-MS analysis

NQO1 and CoQ10 NQO1 is the primary enzyme responsible for reducing ubiquinone (oxidized CoQ10) to ubiquinol (reduced CoQ10) outside the mitochondrial electron transport chain

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Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes: the SURPASS-2 trial