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Cardiovascular (CV)-PASC (chest pain, tachycardia, palpitations)

This activates protein kinase A (PKA), which phosphorylates and stabilizes MITF (microphthalmia-associated transcription factor), driving transcriptional upregulation of tyrosinase, TRP-1, and TRP-2rate-limiting enzymes in the eumelanin biosynthesis pathway (Abdel-Malek et al., Pigment Cell Research, 2001)

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[29,30] Introducing bitters at the beginning of every meal helps your body prepare for the food thats coming, stimulating the pathways and processes that lead to optimal metabolic health