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Mechanistically, cofactor-dependent metabolic nodes illustrate how relatively small reductions in catalytic support can propagate across interconnected pathways involving nucleotide metabolism, redox homeostasis, and immunemetabolic regulation under conditions of metabolic stress [122,123,124,125]

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10.1016/0016-5085(79)90235-x 58 RuenziM.StolteM.VeljacaM.OreskovicK.PetersonJ.Ulcerative Colitis Study Group (2005)

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Accessed July 14, 2025.