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MOMP, cell suicide as a BCL-2 family business

Greenlight Guru founder Jon Speer weighed in on the topic during an interview with The Verge, Class I and Class II products are lower-risk products, a classic Class I example is something like a tongue depressor and its much easier to get clearance than approval. Take the Apple Watch for example, which has garnered a lot of media attention for achieving FDA clearance as a Class II medical device

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Specifically, the peptide upregulated Bcl-2 expression while suppressing Bax, two central regulators of the intrinsic apoptotic pathway