Clinical studies, such as the STEP trials, have shown that adults using semaglutide GLP-1 at the recommended dose (2.4 mg weekly) can lose an average of about 15% of their initial body weight over 68 weeks when combined with healthy lifestyle changes
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GLP-1 agonists and testosterone work on separate hormone pathways, so direct drug interactions are rare
In addition, the low transdermal absorption rate and individual metabolic differences may affect the outcome, and it is necessary to combine scientific lifestyle intervention
What are the main side effects of Mounjaro
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