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J.NierA.et al

Single elevated readings may not indicate problems

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This prolonged retention might increase intragastric pressure and potentially promote retrograde movement of gastric contents into the esophagus, particularly in patients with pre-existing lower esophageal sphincter dysfunction or hiatal hernia

83 In the respiratory tract, they reduce the sensitivity of irritant receptors and antagonize vagally mediated bronchoconstriction

The shared pathological foundation of these diseases is immune system dysfunction, resulting in the overproduction of inflammatory mediators, inappropriate activation of immune cells, and ultimately causing tissue damage (4)