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For people with cobalt allergy (which is more common among people with nickel allergy) who are also at risk of vitamin B12 deficiency, the "general advice seems to be 'take just enough but not too much,' which isn't too different from dosing advice for all vitamins and drugs" (via ACSH)

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( Proposed definitions of status indicators can be found in Addendum D1 to the CY 2026 OPPS/ASC proposed rule

2000 Dec;25(3):287-98