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These experiments highlight the complex and highly dynamic redox landscape of the cell, where individual redox couples, even within a single subcellular compartment, often do not equilibrate with each other in vivo

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This is a mixed review

Also, their potential and progress in an intelligent drug release in response to different types of stimuli either endogenous (pH, redox conditions, and reactive oxygen species (ROS)) or exogenous (temperature, near-infrared (NIR) radiation, and electric field) will be debated