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Key findings for semaglutide duration include continued weight loss through at least 68 weeks with no plateau in many patients, weight regain of approximately 40% of lost weight within seven months of stopping, and withdrawal effects including increased appetite, food cravings, and in some cases gastrointestinal changes

Beumer J, Artegiani B, Post Y, Reimann F, Gribble F, Nguyen TN, et al

I didn't realize how good it would make me feel." Becca K

For both diabetic and non-diabetic patients, the drug can reduce weight (97, 98)

Notably, Wegovy (semaglutide 2.4 mg) now has an additional indication for cardiovascular risk reduction in adults with established cardiovascular disease and either overweight or obesity

Key takeaways Wegovy is administered once weekly on the same day each week through subcutaneous injection into the thigh, abdomen, or upper arm, with sites rotated to prevent skin irritation