It works by stimulating collagen production (up to 70% increase), promoting cellular repair, and resetting aging gene expression to a younger state
This mechanism was also confirmed in subsequent studies
Lussier-Cacan, S
[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Petzer V, Tymoszuk P, Asshoff M, Carvalho J, Papworth J, Deantonio C, Bayliss L, Wake MS, Seifert M, Brigo N, et al
Ubiquitin C-terminal hydrolase-L1 (UCH-L1) shows a similar early increase in blood, and is also detected in cerebrospinal fluid (CSF) throughout 14 days after injury (Svetlov et al., TABLE 3-2 Examples of Biomarkers for TBI 2010)
In yeasts, Yap1 absence renders cells hypersensitive to oxidants generated by superoxide anion radicals