We also found elevated levels of chemokine CXCL1 in females compared to males (main effect of sex: F (1,45) = 5.495, p 2 = 0.109, p = 0.024
Given that ROS that drive ferroptosis is reduced by GSH, the effect of cystine limitation on ferroptosis is mainly ascribed to the loss of antioxidant capacity
Therapeutic strategies aimed at reducing uremic toxin levels, such as the use of intestinal adsorbents or gut microbiota modulators (e.g., probiotics), may help mitigate macrophage-driven vascular inflammation
Taken together, MSG as a food additive could lead to reproductive abnormalities on the molecular, biochemical, and histopathological levels in the male rats
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