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Moreover, IGF-1 stimulates androgen receptor signaling by increasing adrenal and gonadal androgen synthesis as well as androgen receptor transactivation by nuclear extrusion of the androgen receptor cosuppressor FoxO1 [17, 18]

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Wang, A., Shi, W., Zhang, N., Tang, H

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The mice not only maintained blood glucose control and weight loss for up to 15 days after a single treatment, but they actually showed better and more sustained results than those receiving traditional GLP-1 administrationdespite receiving only a quarter of the standard dose

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