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Remarkably, at both doses, tesofensine effectively suppressed this feeding response, significantly reducing cumulative licks compared to saline ( Fig 5C and 5D , see #)

This lack of growth hormone receptor binding explains why AOD-9604 does not affect glucose metabolism, IGF-1 production, or cell proliferation despite being derived from growth hormone

Theoretical or longer-horizon concerns Long-term human safety data for high-dose injectable NAD+ remains limited

Direct head-to-head pharmacokinetic data versus SubQ NAD+ is limited

A licensed provider can help you weigh these factors

Pre-schedule follow-up labs and dose intervals based on your symptoms, not just textbook timelines