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Cutis 2003;71(1):33-34 [PubMed: 12553628] 9

In rodents, semaglutide activates GLP-1 receptors in the thyroid, which stimulates calcitonin release, upregulates expression of the calcitonin gene, and causes hyperplasia of C-cells

5 Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea

Marketed as a minimally invasive solution for targeted fat reduction, this injectable treatment has garnered attention for its purported effectiveness and ease of use

Semaglutide reaches steady state after 4 to 5 weeks of consistent weekly dosing, but it does not continue to build up beyond that point

nonetheless we know that many medicines or lifestyle changes do affect astroglia