These medications should be discontinued before planned conception according to drug-specific guidelines: at least 2 months before for semaglutide, at least 1 month for tirzepatide, and when pregnancy is recognized for other agents
The systematic review protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO), registration number: CRD42024554513 (Available from) (NIHR, 2025)
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Women using hormonal contraceptives or in specific menstrual cycle phases may experience variability in GH response tracking IGF-1 at consistent cycle points (follicular phase) provides more reliable trend data
GLP-1: The Weight of Speculation