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With a molecular weight of just 403.93 Da well below the 500 Da cutoff typically associated with significant skin penetration GHK-Cu is small enough to penetrate the stratum corneum (outer skin layer) in concentrations sufficient to activate regenerative processes

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Low vitamin B12 can lead to multiple dermatological symptoms such as hyperpigmentation, discoloration of nails, vitiligo, changes in hair, and angular stomatitis

[DOI] [PubMed] [Google Scholar] 18.Seiwerth S., Milavic M., Vukojevic J., Gojkovic S., Krezic I., Vuletic L.B., Pavlov K.H., Petrovic A., Sikiric S., Vranes H., et al