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5,6 Adjacency to a big vessel or nerve trunk makes EMPNST unresectable and recurrence with distant metastasis make this tumor fatal

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Keywords Cocaine Street Names: Coke, Flake, Snow, Blow, Toot, Base, Nose Candy, C, Line & numerous others Drug Class: DEA Schedule II: Topical Local anesthetic (Goprelto ) CNS stimulant & Drug of Abuse Mechanism of Action: Low concentrations block monoamine reuptake transport into nerve terminals (All three types: NET, DAT & SERT) (Kd 0.3 uM for NET) (Figure 1)

Folinic acid promotes methylation reactions crucial for gene regulation and detoxification

Asela Russell, M.D