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A 2-year observational study that included 168 CKD patients demonstrated that participants with the lowest vitamin D levels had a faster rate of CKD progression and shorter time to kidney failure and death

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Generally, canonical Wnt cascades such as Wnt3a can stimulate insulin secretion and enhance the proliferation of cell by activating -catenin/TCF/LEF-mediated Cyclin D1 transcription

Integration of multi-omics approaches in exploring intra-tumoral heterogeneity