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2 GPX family and oxidative stress 2.1 GPX1 Glutathione peroxidase 1 (GPX1) was first identified in 1957 as a red blood cell enzyme that protects hemoglobin from oxidative stress (MILLS, 1957)

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Furthermore, numerous NCI-60 cell lines (60 human cancer cell lines used by the National Cancer Institute) were purchased from the National Cancer Institutes Developmental Therapeutics Program (NCI), including Hop62 (a human lung adenocarcinoma epithelial cell line), Hop92 (a human lung non-small lung cancer cell line), H1650 (a human lung adenocarcinoma epithelial cell line), H23 (a human lung adenocarcinoma epithelial cell line), and H460 (a human lung non-small lung cancer cell line)