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This pattern is most common during the first 1-2 weeks on tirzepatide and during dose escalation periods

Another group of methods gaining popularity are those based on immunoassay tests

10.1016/S0960-9822(03)00250-1 267 YadavV

The researchers identified a phenomenon called GLP-1 resistance, in which the body produces higher levels of the hormone GLP-1 (glucagon-like peptide-1) but fails to respond to it properly