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may have important implications on the accessibility and adherence of these drugs in the future, [because] currently all agents approved for weight loss are injections. The results showed frequent adverse events during the trials, ranging from 80% to 97% for GLP-1 receptor agonists and coagonists and 63% to 100% for placebo

Its main physiological roles include stimulating insulin release in a glucose-dependent manner, suppressing glucagon, slowing gastric emptying, and reducing appetite

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Patients had a nine times greater likelihood of bowel obstruction